As Woodman's secretary, Karen is often seen helping him move his wheelchair. She is in love with him and is not afraid of confessing her feelings in front of him or anyone else.
Karen is currently not on good terms with her sister. She tells Elliot that she understood years ago that she and her sister would not get along after Elliot told her that a future confrontation with DEM was inevitable.
Due to her and Origami's similar personalities, the two quickly bonded. After Origami complimented her resolve of her love and dedication towards Elliot, Karen, in return, thanked the former AST wizard for the praise. She reveals that Origami is the second person to have said that about her.